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. 2023 Apr 14;18:82. doi: 10.1186/s13023-023-02669-7

Table 2.

Comorbidities and most frequent symptoms causing main discomfort

Most common comorbidities reported by patients (n = 142) n (%) 10 symptoms most frequently mentioned as main discomfort1 (n = 130) n (%)
Allergies/ intolerances 71 (50.4) Fatigue 37 (28.5)
Thyroid disease 48 (34.0) Loss of productivity 28 (21.5)
Diseases of the skeletal system 47 (33.3) Pain arms, hands, legs, feet 24 (18.5)
Respiratory disease 41 (29.1) Muscular pain 20 (15.4)
Diseases of the digestive system 36 (25.5) Joint pain 14 (10.8)
Eye disease 33 (23.4) Irritation of the skin 14 (10.8)
Disease of the circulatory system 29 (20.6) Muscle weakness 13 (10.0)
Renal and urinary tract disease 25 (17.7) Stomachache 12 (9.2)
Neurological disease 25 (17.7) Headache 12 (9.2)
Psychological disorder 24 (17.0) Increased need for sleep 12 (9.2)
Heart disease 21 (14.9) Dyspnea 11 (8.5)
Blood disease 20 (14.2)
Metabolic disease 18 (12.8)
Diseases of the muscular system 13 (9.2)
Liver disease 8 (5.7)

1 Patients were asked to name 3 symptoms mainly causing discomfort