Table 2.
Standard prolonged intermittent KRT prescriptions with continuous KRT and hemodialysis machines
| Variable | CKRT Machines | Hemodialysis Machines |
|---|---|---|
| Duration of treatment | 8–12 hr | 8–12 hr |
| Frequency of treatment | 4–7 d/wka | 3–7 d/wk |
| Dialysate flow rateb | 66–133 ml/minc | 200 ml/min |
| Blood flow rate | 200–400 ml/min | 200–400 ml/min |
| Ultrafiltration rate | Depending on volume and hemodynamic status | Depending on volume and hemodynamic status |
CKRT, continuous KRT; PIKRT, prolonged intermittent KRT.
a
Clearance using CKRT equipment is lower than with intermittent HD equipment; 3 days per week will not provide adequate clearance.
b
During PIKRT with CKRT equipment, therapy fluid can be delivered as either dialysate (diffusive clearance) or replacement fluid (convective clearance).
c
Dialysate flow rate calculated on the basis of CKRT flow rates. Recommended CKRT flow rate is 20–25 ml/kg per hour. For example, for 100 kg, 20 ml/kg per hour = 48,000 ml in 24 hours. For 8-hour PIKRT, divide 48,000 ml by 8 hours = 6000 ml/hour = 100 ml/min.