Table 5.
Effect of Aqueous Extract of Garcinia cambogia on Liver Function Markers.
| Parameters | Normal control | PCOS | Metformin | G.C 100 mg/kg | G.C 300 mg/kg | G.C 500 mg/kg |
|---|---|---|---|---|---|---|
| (ALT) (U/L) | 50.57 ± 1.11 | 73.00 ± 2.309 a*** | 81.66 ± 1.45 a***b** | 63.33 ± 1.9 ab*** | 56.66 ± .2 b*** | 48.000 ± .7 bc*** |
| (AST) (U/L) | 257.2 ± 11.39 | 298.8 ± 2.02 a*** | 428.00 ± 4.05 ab*** | 290.00 ± 1.63 a***b** | 261.2 ± 1.4 bc** | 185.000 ± .7 abc*** |
| Alkaline phosphatase (U/l) | 376.00 ± .33 | 450.80 ± 2.08 a*** | 429.00 ± 1.45 ab*** | 440.8 ± 1.5 ab*** | 421.88 ± 1.158 abc*** | 307.66 ± 1.4 abc*** |
| Total Bilirubin (mg/dL) | .734 ± .00 | .806 ± .00 a*** | .704 ± .003 ab*** | .708 ± .003 ab*** | .710 ± .005 ab*** | .508 ± .0006 abc*** |
| Direct Bilirubin (mg/dL) | .198 ± .00 | .304 ± .00 a*** | 302 ± .00 a*** | .304 ± .006 a*** | 0.280 ± .01 bc*** | .210 ± .00A abc*** |
| Indirect Bilirubin (mg/dL) | .402 ± .00 | .502 ± .00 a*** | 402 ± .003 b*** | .402 ± .003 b*** | .308 ± .005 abc*** | .302 ± .003 abc*** |
Values are expressed as mean ± SEM (n = 5). adenotes significant difference from Normal Control; bdenotes significant difference from Disease Control (PCOS); cdenotes significant difference from AEGC 100 mg/kg; results were compared by one-way ANOVA followed by Tukey’s multiple comparisons test. *P < .05, **P < .01, ***P < .001.