Figure 4.

Anti‐C5 plus anti‐CD40 prolongs renal xenograft survival. (A) Creatinine is shown to be well controlled until acutely rising at time of graft failure. (B) Serum potassium was well controlled throughout, except during late graft failure because of rejection. (C) Early graft failure recipients encounter anemia as shown by decreased hemoglobin levels. Tesidolumab-treated recipients maintained hemoglobin levels at or above normal levels more frequently than control animals for the duration of graft survival.