Table 2.
Baseline characteristics by WHtR groups
| Characteristics | WHtR groups | P-value | P for linear trend | |||
|---|---|---|---|---|---|---|
| < 0.47 | 0.47- < 0.52 | 0.52- < 0.57 | ≥ 0.57 | |||
| N | 1169 | 1316 | 1190 | 1130 | ||
| Age (years), median (IQR) | 65 (57–74) | 64 (56–72) | 63 (55–70) | 63 (55–71) | < 0.0001 | < 0.0001 |
| Male, N (%) | 824 (70.49%) | 943 (71.66%) | 790 (66.39%) | 657 (58.14%) | < 0.0001 | < 0.0001 |
| Ethnicity(Han), N (%) | 1140 (97.52%) | 1264 (96.05%) | 1130 (94.96%) | 1049 (92.83%) | < 0.0001 | < 0.0001 |
| Stroke history, N (%) | 192 (16.42%) | 269 (20.44%) | 237 (19.92%) | 234 (20.71%) | 0.0297 | 0.0191 |
| Medical comorbidities, N (%) | ||||||
| Diabetes mellitus | 279 (23.87%) | 274 (20.82%) | 268 (22.52%) | 286 (25.31%) | 0.0558 | 0.2682 |
| Atrial fibrillation | 111 (9.50%) | 108 (8.21%) | 102 (8.57%) | 63 (5.58%) | 0.0042 | 0.0016 |
| Myocardial infarction | 19 (1.63%) | 14 (1.06%) | 22 (1.85%) | 18 (1.59%) | 0.4208 | 0.6407 |
| Hypertension | 711 (60.82%) | 819 (62.23%) | 776 (65.21%) | 801 (70.88%) | < 0.0001 | < 0.0001 |
| Lipid metabolism disorders | 64 (5.47%) | 71 (5.40%) | 94 (7.90%) | 101 (8.94%) | 0.0005 | < 0.0001 |
| Heavy drinkinga, N (%) | 134 (11.46%) | 188 (14.29%) | 140 (11.76%) | 130 (11.50%) | 0.0882 | 0.5481 |
| Current smoker, N (%) | 315 (26.95%) | 419 (31.84%) | 359 (30.17%) | 296 (26.19%) | 0.0054 | 0.4982 |
| Body mass index, median (IQR) | 22.84 (20.76–24.80) | 23.44 (21.72–25.12) | 24.68 (23.05–26.36) | 26.71 (24.49–29.05) | < 0.0001 | < 0.0001 |
| TOAST subtypes, N (%) | ||||||
| Large-artery atherosclerosis | 281 (24.04%) | 347 (26.37%) | 298 (25.04%) | 298 (26.37%) | 0.0575 | |
| Small-vessel occlusion | 233 (19.93%) | 270 (20.52%) | 269 (22.61%) | 276 (24.42%) | ||
| Cardioembolism | 97 (8.30%) | 91 (6.91%) | 94 (7.90%) | 59 (5.22%) | ||
| Stroke of other determined etiology | 21 (1.80%) | 21 (1.60%) | 20 (1.68%) | 15 (1.33%) | ||
| Stroke of undetermined etiology | 537 (45.94%) | 587 (44.60%) | 509 (42.77%) | 482 (42.65%) | ||
| NIHSS at admission, median (IQR) | 3 (2–6) | 3 (2–6) | 3 (2–6) | 3 (2–6) | 0.0832 | 0.0609 |
| Intravenous thrombolysis, N (%) | 143 (12.23%) | 171 (12.99%) | 128 (10.76%) | 94 (8.32%) | 0.0016 | 0.0007 |
| Arterial thrombolysis or mechanical thrombectomy, N (%) | 12 (1.03%) | 10 (0.76%) | 4 (0.34%) | 2 (0.18%) | 0.0274 | 0.0028 |
Kruskal–Wallis test was used to compare group differences for continuous variables, and χ2 test was used for categorical variables. P for linear trend was calculated by Kendall's Tau-b correlation analysis for continuous variables or Cochran-Armitage test for categorical variables. aHeavy drinking was defined as alcohol consumption ≥ 2 standard alcohol consumption /day. WHtR, waist-to-height ratio; TOAST, Trial of Org 10172 in Acute Stroke Treatment; NIHSS, National Institutes of Health Stroke Scale