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. Author manuscript; available in PMC: 2023 Apr 14.
Published in final edited form as: Behav Genet. 2022 Jun 8;52(4-5):268–280. doi: 10.1007/s10519-022-10104-z

Table II.

Base model R2 and PRS Change R2 across TOB models.

Base Model Base Model R2 Change R2 with PRS Percent Change
~ Ancestry PCs 0.013 0.020
~ Ancestry PCs + TOB 0.181 0.010 50%
~ Ancestry PCs + TOB + Phenotypic PCs 0.562 0.017 35%

PRS = polygenic risk score; TOB = tobacco use; PCs = principal components