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. 2023 Apr 14;15:25. doi: 10.1186/s13073-023-01177-4

Table 2.

Swedish Breast Cancer Group criteria for screening for variants in predisposition genes as implemented in 2017 and how many patients meet those criteria in SCAN-B. Criteria from before 2017 are available in [32]

Criteria SCAN-B casesb
Breast cancer ≤ 40 years of age 329
Breast cancer ≤ 50 years of age if there is at least one other case of breast cancer in first-degree or second-degree relativesa NA
Breast cancer ≤ 60 years of age if there are at least two other cases of breast cancer in first-degree or second-degree relativesa NA
Triple-negative breast cancer ≤ 60 years of age 298
Male breast cancer irrespective of age 48
Ovarian cancer including fallopian tube cancer and primary peritoneal carcinomatosis (not mucinous nor borderline) irrespective of age NA
Meeting criteria for other hereditary syndromes that include breast/ovarian cancer NA

a The other cancer cases can also be of ovarian cancer, early prostate cancer (before the age of 65), or pancreatic cancer. Bilateral breast cancer counts as two cases.

b NA number of patients could not be calculated since family history was not accessible to the study