Table 2.
Swedish Breast Cancer Group criteria for screening for variants in predisposition genes as implemented in 2017 and how many patients meet those criteria in SCAN-B. Criteria from before 2017 are available in [32]
| Criteria | SCAN-B casesb |
|---|---|
| Breast cancer ≤ 40 years of age | 329 |
| Breast cancer ≤ 50 years of age if there is at least one other case of breast cancer in first-degree or second-degree relativesa | NA |
| Breast cancer ≤ 60 years of age if there are at least two other cases of breast cancer in first-degree or second-degree relativesa | NA |
| Triple-negative breast cancer ≤ 60 years of age | 298 |
| Male breast cancer irrespective of age | 48 |
| Ovarian cancer including fallopian tube cancer and primary peritoneal carcinomatosis (not mucinous nor borderline) irrespective of age | NA |
| Meeting criteria for other hereditary syndromes that include breast/ovarian cancer | NA |
a The other cancer cases can also be of ovarian cancer, early prostate cancer (before the age of 65), or pancreatic cancer. Bilateral breast cancer counts as two cases.
b NA number of patients could not be calculated since family history was not accessible to the study