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. 2023 Apr 14;2023(4):CD007986. doi: 10.1002/14651858.CD007986.pub3

NCT01807299.

Study characteristics
Methods Design: parallel trial
Comparison: omega‐3 PUFA + physical training vs placebo + physical training
Participants Inclusion criteria: 1. children aged 7 to 14 years with ADHD; 2. boys; 3. sedentary; 4. studying in a regular school
Exclusion criteria: 1. taking psychoactive medications; 2. taking omega supplement
Number of participants: 53 (47 completed)
Mean age: 10.51 years
Gender: all 53 participants were male
ADHD subtypes: not stated
Using ADHD drugs at baseline: 0%
Baseline Conners scores: omega‐3 = 36.64; omega‐3 + physical training = 36.82; control = 42.31; control + physical training = 40.08
Setting: school, Brazil, year/s not stated
Funding: not stated
Interventions Intervention (22 participants): capsules of omega‐3, 2 g per day of fish oil for 90 days +/‐ physical training
Control (25 participants): 2 g per day of mineral oil +/‐ physical training for 90 days
Outcomes
  1. ADHD symptoms at 3 months (rater not stated)

    1. Conners Rating Scale

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias)
All outcomes Unclear risk Not stated
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not stated
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Not stated
Selective reporting (reporting bias) Low risk All relevant outcomes were reported
Other bias Unclear risk PUFA and control groups were similar for age, gender ethnicity and baseline scores