Table 1.
Demographics and characteristics for participants enrolled in the longitudinal analysis of mucosal barrier properties and vaginal microbiome during pregnancy.
| Pregnancy demographics | Total Cohort (n=92) | Term (n=82) |
Preterm (n=10) |
Relative Risk |
Odds Ratio |
95% CI | p Value |
|---|---|---|---|---|---|---|---|
| Median (range) | |||||||
| Age | 28.8 (18-41) | 28.9 (18-41) | 28.3 (22-35) | ||||
| BMI | 29.9 (18-64) | 30 (18-64) | 28.8 (22-38) | ||||
| Weeks at delivery | 38.7 (27-43) | 39.3 (37-43) | 34.4 (27-37) | ||||
| Ethnicity | Number (%) | ||||||
| Hispanic or Latina | 24 (26) | 22 (27) | 2 (20) | 0.7083 | 0.6818 | 0.14 to 3.3 | >0.999 |
| Race | Number (%) | ||||||
| White | 40 (43) | 39 (48) | 1 (10) | 0.144 | 0.123 | 0.011-0.84 | 0.039 |
| Black or African American | 25 (27) | 18 (22) | 7 (70) | 6.25 | 8.296 | 0.032-0.53 | 0.004 |
| Asian | 4 (4) | 4 (5) | 0 (0) | 0 | 0 | 0.0-9.55 | >0.999 |
| Other | 23 (25) | 21 (26) | 2 (20) | 0.781 | 0.726 | 0.146-3.5 | >0.999 |
| History of conditions | Number (%) | ||||||
| None | 68 (74) | 63 (77) | 5 (50) | 0.353 | 0.302 | 0.085-1.09 | 0.12 |
| Yes, specified (see below) |
24 (26) | 19 (23) | 5 (50) | 2.833 | 3.32 | 0.919-11.77 | 0.12 |
| HIV | 2 (2) | 1 (1) | 1 (10) | 5 | 9 | 0.429-172.1 | 0.21 |
| Herpes | 6 (7) | 5 (6) | 1 (10) | 1.59 | 1.71 | 0.132-11.75 | 0.51 |
| Gonorrhea | 3 (3) | 1 (1) | 2 (20) | 7.42 | 20.25 | 2.03-294.8 | 0.03 |
| Chlamydia | 10 (11) | 7 (9) | 3 (30) | 3.51 | 4.59 | 1.074-19.81 | 0.075 |
| Bacterial vaginosis (BV) | 13 (14) | 10 (12) | 3 (30) | 2.6 | 3.09 | 0.758-11.82 | 0.147 |
| Syphilis | 1 (1) | 1 (1) | 0 (0) | 0 | 0 | 0.0-73.80 | >0.999 |
| Trichomoniasis | 9 (10) | 8 (10) | 1 (10) | 1.03 | 1.03 | 0.0841-7.19 | >0.999 |
| History of experiences | Number (%) | ||||||
| Previous pregnancy | 71 (77) | 68 (83) | 3 (30) | 0.127 | 0.088 | 0.038-0.419 | 0.0010 |
| Previous PTB | 7 (8) | 5 (6) | 2 (20) | 3.04 | 3.85 | 0.67-20.98 | 0.166 |
| Previous miscarriage | 26 (28) | 23 (28) | 3 (30) | 1.09 | 1.10 | 0.29-4.63 | >0.999 |
| Previous BV | 18 (20) | 16 (20) | 2 (20) | 2.60 | 3.09 | 0.76-11.82 | 0.147 |
| Previous short cervix | 1 (1) | 1 (1) | 0 (0) | 0 | 0 | 0.0-73.8 | >0.999 |
| Previous low birth weight | 4 (4) | 4 (5) | 0 (0) | 0 | 0 | 0.0-9.55 | >0.999 |
| Previously homeless | 26 (28) | 22 (27) | 4 (40) | 1.69 | 1.82 | 0.53-6.37 | 0.460 |
| Experienced intimate partner violence | 35 (38) | 30 (37) | 5 (50) | 1.62 | 1.73 | 0.50-5.94 | 0.496 |
| Current pregnancy experiences | Number (%) | ||||||
| BV Symptoms | 16 (17) | 15 (18) | 1 (10) | 0.5278 | 0.4963 | 0.04263-3.762 | >0.9999 |
| BV Treatment | 9 (10) | 9 (11) | 0 (0) | 0 | 0 | 0.0-3.669 | 0.5897 |
| High risk | 48 (52) | 43 (52) | 5 (50) | 0.9167 | 0.907 | 0.2661-3.096 | >0.9999 |
| Addiction counseling | 41 (45) | 38 (46) | 3 (30) | 0.5331 | 0.4962 | 0.1332-2.026 | 0.5029 |
| Smoking | 40 (43) | 38 (46) | 2 (20) | 0.325 | 0.2895 | 0.05965-1.339 | 0.1774 |
| Male baby | 47 (51) | 40 (49) | 7 (70) | 2.234 | 2.45 | 0.6000-9.109 | 0.3167 |
Significance is indicated by a bolded p Value.