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. 2023 Feb 14;11(2):e03361-22. doi: 10.1128/spectrum.03361-22

TABLE 3.

Strain tolerance to artificial gastric fluid, artificial intestinal fluid, and bile salts

Fluid or salts exposure Incubation time (h) % Survival (mean ± SD) of indicated strain
ATCC BAA-835 AM01 AM02 AM03 AM04 AM05 AM06
Artificial gastric fluid
 pH 3 1.5 9.77 ± 2.89 84.88 ± 10.07 15.4 ± 12.02 0.18 ± 0.03 34.14 ± 1.76 10.98 ± 1.26 74.97 ± 2.25
3 2.37 ± 0.58 57.75 ± 8.42 3.71 ± 1.65 0.02 ± 0 9.95 ± 1.38 1.42 ± 0.11 24.4 ± 8.3
 pH 2 1.5 14.42 ± 3.79 66.04 ± 18.51 5.63 ± 3.06 31.45 ± 12.09 4.76 ± 1.43 2.43 ± 1.02 15.56 ± 1.39
3 9.29 ± 3.22 53.20 ± 18.93 2.74 ± 1.16 3.15 ± 1.21 1.87 ± 0.45 1.17 ± 0.32 10.74 ± 1.17
Artificial intestinal fluid
 pH 6.8 4 82.83 ± 1.86 88.13 ± 5.01 79.99 ± 11.89 84.74 ± 7.78 89.35 ± 13.17 129.47 ± 11.61 102.17 ± 12.17
8 88.75 ± 9.34 107.58 ± 4.83 51.03 ± 10.80 50.435 ± 5.88 124.66 ± 13.14 117.08 ± 9.31 125.27 ± 29.88
Bile salts
 0.5% 4 100.49 ± 10.83 87.96 ± 29.70 101.25 ± 3.20 95.45 ± 8.53 92.73 ± 16.38 123.85 ± 6.98 113.73 ± 12.58
8 61.83 ± 1.82 70.60 ± 9.90 76.56 ± 2.41 99.47 ± 4.60 144.03 ± 47.64 112.88 ± 7.91 88.47 ± 21.98
 1% 4 79.68 ± 5.80 65.02 ± 6.25 84.93 ± 2.49 117.09 ± 9.44 114.96 ± 39.2 114.58 ± 8.52 88.64 ± 7.56
8 50.57 ± 10.67 49.10 ± 2.83 62.15 ± 2.31 92.83 ± 2.56 106.99 ± 20.92 80.37 ± 12.02 131.31 ± 10.11