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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Cardiovasc Intervent Radiol. 2022 Apr 22;45(7):958–969. doi: 10.1007/s00270-022-03139-6

Figure 2.

Figure 2.

Optimal particle density depends on tumor vascularity. Graphs show local progression-free survival, for hypervascular (A) or less vascular (B) tumors, treated with high particle density (HPD; red) versus low particle density (LPD; blue) radioembolization. For hypervascular tumors (T:N ratio ≥ 2.6), delivering fewer particles (<6000 particles/cm3) was associated with better LPFS (p=0.03). For less vascular tumors (T:N ratio < 2.6), delivering more particles (≥6000 particles/cm3) was associated with better LPFS (p=0.02). The T:N ratio was measured on the MAA scan. The particle density refers to the mean particle density over the entire treatment volume. The differences in optimal particle density for hypervascular versus less vascular tumors could be explained by the changes in T:N ratios as more particles are delivered (Figure 3, Table 2).