Table IV:
Relative prevalence of selected crucial laboratory abnormalities calculated using regression analysis. "corrected calcium = serum calcium + 0.8 (4 - serum albumin)", taking 4gm/dl albumin as the reference value
Variable | Group-L n/N (%) | Group-H n/N (%) | PR (95% CI) | P-value |
---|---|---|---|---|
Hypercalcemia (>10.4mg/dl) | 23/122 (18.9) | 6/37 (16.2%) | 1.2 (0.4-3.2) | 0.72 |
Hyperphosphatemia (>4.7mg/dl) | 11/123 (8.9%) | 4/36 (11.1%) | 0.8 (0.2-2.6) | 0.70 |
Hyperparathyroidism (>66pg/ml) | 9/108 (8.3%) | 2/39 (5.1%) | 1.7 (0.3-8.1) | 0.73 |
Vitamin D deficiency (<20ng/ml) | 18/106 (17.0%) | 7/38 (18.4%) | 0.9 (0.3-2.4) | 0.84 |
eGFRcr <60 | 7/117 (6.0 %) | 5/36 (13.9%) | 0.4 (0.1-1.3) | 0.12 |
Raised ALP (>129IU/L) | 19/122 (15.6%) | 2/36 (5.6%) | 3.1 (0.7-14.1) | 0.16 |
Hypoalbuminemia (<3.4gm/dl) | 19/119 (16.0%) | 8/37 (21.6%) | 0.7 (0.3-1.7) | 0.43 |
Raised AST (>40IU/L) | 13/121 (10.7%) | 2/37 (5.4%) | 2.1 (0.5-9.8) | 0.34 |
Raised ALT (>45IU/L) | 10/121 (8.3%) | 3/37 (8.1%) | 1.0 (0.3-3.9) | 1.0 |
Anaemia (<10gm/dl) | 14/120 (11.7%) | 6/37 (16.2%) | 0.7 (0.2-1.9) | 0.47 |
Abnormal Sodium (>148 or <135mmol/L) | 28/122 (23.0%) | 9/37 (24.3%) | 0.9 (0.4-2.2) | 0.86 |
Abnormal Potassium (>5 or <3.5mmol/L) | 24/121 (19.8%) | 7/37 (18.9%) | 1.0 (0.4-2.7) | 0.90 |
At least one selected parameter | 89/124 (71.8%) | 30/49 (61.2%) | 1.6 (0.8-3.2) | 0.18 |
Abbreviations - n: number of patients qualifying the criteria, N: number of patients whose data were available. ALT: Alanine aminotransferase, ALP: Alkaline phosphatase, AST: Aspartate aminotransferase, CI: Confidence interval, eGFRcr: Estimated glomerular filtration rate based on the serum creatinine, PR: Prevalence ratio.