Figure 5. Motifs enriched in joint metaclusters.

The top heatmap shows the enrichment of motifs in the cCREs in each JmC in human (H) and mouse (M) as a Z-score. The logo for each motif is given to the right of the heat map, labeled by the family of transcription factors that recognize that motif. The heatmap below is aligned with the motif enrichment heatmap, showing the mean esRP score for the cCREs in each JmC for all the common cell types examined between human and mouse. A summary description of the cell types in which the cCREs in each JmC are more active is given at the bottom.