Figure 5 |. ECs ex vivo human atherosclerotic plaques are distinguished by EndMT.

(A), scRNA-seq UMAP of different cell subtypes across 17 samples of ex vivo human atherosclerotic plaques. (B), Dot plot of top markers for each cell type. The size of the dot represents the percentage of cells within each cell subtype that express the given gene, while the shade of the dot represents the level of average expression (“Avg. Expn.” in the legend). (C), Heatmap of pathway enrichment analysis (PEA) results generated from submitting 200 differentially expressed genes (DEGs) between Endothelial Cells 1 (Endol) and Endothelial Cells 2 (Endo2). Rows (pathways) and columns (cell subtypes) are clustered based on −Log₁₀(P). (E), Heatmap displaying expression of genes belonging to ribosome cytoplasmic pathway for Endol and Endo2.