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[Preprint]. 2023 Apr 4:2023.04.03.23288056. [Version 1] doi: 10.1101/2023.04.03.23288056

Figure 4. Bar chart showing the predictive accuracy of the RTV-PGS in three independent cohorts.

Figure 4.

Prediction of RTV by polygenic score (PGS) in the African, non-British European, and South Asian ancestry groups from the UK Biobank. The predictive accuracy of the PGS (R2) was assessed in each cohort for a PGS calculated using two methodologies, PRSice and PRS-CS. PRSice PGS were calculated using all single nucleotide polymorphisms surviving LD pruning from the discovery GWAS (p-value threshold of 1).

*p<0.05, ***p<2.63 x 10−3