Table 1.

Genome-wide significant loci for the discovery GWAS of RTV in 404,302 individuals

Genomic Risk Locus	Lead Variant	Chr	Position	A1/A2	Discovery GWAS					Replication GWAS
					A1 Freq	Beta	P-value	Top Assigned Gene	Nearest Gene	Beta	P-value
1	rs183204237	2	162188514	C/G	9.790⍰×⍰10−4	−0.21	2.340⍰×⍰10−8	PSMD14	PSMD14	−0.088	0.46
2	rs35206686	4	152762934	T/TC	0.736	−0.015	6.090⍰×⍰10−9	FHIP1A	RP11-424M21	−0.004	0.615
3	rs17167210	7	133339343	A/G	0.435	0.013	1.5⍰×⍰10−9	EXOC4	EXOC4	−0.01	0.141
4	rs35859241	15	51736660	G/A	0.254	−0.014	3.69⍰×⍰10−8	SCG3	RP11-707P17.1	−0.001	0.864
5	rs912243472	15	74096786	G/GA	0.135	0.018	1.97⍰×⍰10−8	TBC1D21	INSYN1	0.005	0.575
6	rs1863115	17	44625928	A/C	0.74	0.017	2.47x10−10	LRRC37A2	LRRC37A2	0.003	0.755
7	rs11697176	20	3831629	T/C	0.112	−0.021	1.9⍰×⍰10−8	PANK2	MAVS	0.008	0.58