Table 1.
Distribution of baseline sample characteristics by dementia status after 6-year of follow-up, United States Health and Retirement Study, 2006 and 2008
| Characteristic | Overall sample N = 5,1431 |
Incident dementia N = 7951 |
Cognitively normal N = 43481 |
p-value2 |
|---|---|---|---|---|
| Baseline CRP (μg/mL) | 4.18 (7.70) | 5.13 (11.28) | 4.00 (6.83) | <0.001 |
| Age (years) | 66.36 (9.90) | 75.64 (9.62) | 64.66 (8.97) | <0.001 |
| Race | <0.001 | |||
| Non-Hispanic Black | 488 (9.5%) | 171 (22%) | 317 (7.3%) | |
| Hispanic | 376 (7.3%) | 103 (13%) | 273 (6.3%) | |
| Non-Hispanic White | 4,279 (83%) | 521 (66%) | 3,758 (86%) | |
| Sex | 0.235 | |||
| Female | 3,189 (62%) | 478 (60%) | 2,711 (62%) | |
| Male | 1,954 (38%) | 317 (40%) | 1,637 (38%) | |
| Educational Category | <0.001 | |||
| > College | 602 (12%) | 25 (3.1%) | 577 (13%) | |
| College/Some | 1,109 (22%) | 68 (8.6%) | 1,041 (24%) | |
| HS or < | 3,432 (67%) | 702 (88%) | 2,730 (63%) | |
| Alcohol (# drinks/day when drinks) | 0.74 (1.27) | 0.40 (1.07) | 0.80 (1.29) | <0.001 |
| Smoking Status | 0.168 | |||
| Current/Former | 2,835 (55%) | 456 (57%) | 2,379 (55%) | |
| Never | 2,308 (45%) | 339 (43%) | 1,969 (45%) | |
| Body Mass Index (kg/m2) | 28.46 (5.75) | 27.17 (5.38) | 28.69 (5.78) | <0.001 |
| Chronic Conditions | <0.001 | |||
| At least 1 | 4,223 (82%) | 719 (90.4%) | 3,504 (81 %) | |
| No | 920 (18%) | 76 (9.6%) | 844 (19%) | |
| APOE-ε4 | <0.001 | |||
| At least 1 copy | 1,363 (27%) | 258 (32%) | 1,105 (25%) | |
| No copy | 3,780 (73%) | 537 (68%) | 3,243 (75%) | |
| Time (years) | <0.001 | |||
| 2 | 302 (5.9%) | 302 (38%) | 0 (0%) | |
| 4 | 269 (5.1%) | 269 (34%) | 0 (0%) | |
| 6 | 4,572 (89%) | 224 (28%) | 4,348 (100%) | |
| Wave | <0.001 | |||
| 2006 | 2,597 (50%) | 339 (43%) | 2,258 (52%) | |
| 2008 | 2,546 (50%) | 456 (57%) | 2,090 (48%) |
1
Mean (SD); n (%)
2
One-way ANOVA; Pearson’s Chi-squared test
CRP: C-reactive protein; APOE-ε4: apolipoprotein E ε4 allele carrier status