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. 2023 Apr 14;18(4):e0284323. doi: 10.1371/journal.pone.0284323

Table 1. Distribution of hepatitis B and C seroprevalence, sociodemographic, and behavioral characteristics by antipsychotic medication use from the 2005–2014 National Health and Nutrition Examination Survey (n = 12,722).

Characteristic Antipsychotic use No Antipsychotic Use p a
(n = 163) (n = 12,559)
Wtd. % (Unwtd. n) Wtd. % (Unwtd. n)
Hepatitis B core antibody, % (n) 0.11
 HBV positive 5.9% (16) 3.7% (637)
 HBV negative 94.1% (147) 96.3% (11,922)
Hepatitis C virus antibody, % (n) <0.001
 HCV positive 5.3% (13) 1.6% (216)
 HCV negative 94.7% (150) 98.4% (12,343)
Age, M [95% CI] 41.6 [39.4, 43.8] 39.1 [38.7, 39.5] <0.05
Sex, % (n) 0.31
 Male 54.1% (82) 49.2% (6,057)
 Female 45.9% (81) 50.8% (6,502)
Race, % (n) 0.08
 Non-Hispanic White 72.5% (93) 67.9% (5,548)
 Non-Hispanic Black 13.7% (35) 11.1% (2,609)
 Hispanic 8.4% (24) 14.5% (3,229)
 All other races 5.3% (11) 6.5% (1,173)
Immigrant status, % (n) <0.01
 Born in United States 93.0% (142) 83.4% (9,301)
 Born outside United States 7.0% (21) 16.6% (3,258)
Marital status, % (n) <0.001
 Married or cohabitating 46.5% (65) 64.0% (7,657)
 Never married 38.0% (65) 22.5% (3,096)
 Widowed, divorced, or separated 15.5% (33) 13.5% (1,806)
Education, % (n) 0.06
 College 54.7% (77) 65.0% (7,288)
 High school graduate 26.1% (41) 21.2% (2,725)
 Less than high school 19.2% (45) 13.8% (2,546)
Income, M [95% CI]b 2.26 [1.95, 2.58] 3.11 [3.02, 3.19] <0.001
Blood transfusion, % (n) <0.05
 Yes 11.4% (25) 6.3% (830)
 No 88.7% (138) 93.7% (11,729)
Alcohol use, % (n) 0.33
 Yes 36.4% (48) 41.9% (4,864)
 No 63.6% (115) 58.1% (7,695)
Injection drug use, % (n) <0.001
 Yes 9.2% (12) 2.1% (253)
 No 90.8% (151) 97.9% (12,306)
Sexually transmitted infection, % (n) <0.05
 Yes 3.2% (6) 1.0% (156)
 No 96.8% (157) 99.0% (12,403)

Notes: Wtd. = weighted; Unwtd. = unweighted; M = mean; CI = confidence interval;

aPearson’s chi-square for categorial and t test for continuous predictors;

bIncome is measured by the ratio of family income to the federal poverty lines, with values from 0 to 5. A value of “0” represents no income and a value of “5” represents an income greater than or equal to 500% of the federal poverty line.