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. 2023 Apr 14;18(4):e0284323. doi: 10.1371/journal.pone.0284323

Table 2. Unadjusted and adjusted prevalence odds ratios, with 95% confidence intervals (CI), of the association between antipsychotic medication use and antibody to hepatitis B virus (HBV) among respondents to the 2005–2014 National Health and Nutrition Examination Survey (n = 12,722).

Characteristic Unadjusted Adjusted
OR [95% CI] p aOR [95% CI] p
Antipsychotic Use
 Yes 1.64 [0.89, 3.02] 0.11 1.01 [0.50, 2.02] 0.98
 No 1.00 Ref. 1.00 Ref.
Age, M [95% CI] 1.06 [1.05, 1.07] <0.001
Sex, % (n)
 Male 1.00 Ref.
 Female 0.73 [0.60, 0.89] <0.05
Race, % (n)
 Non-Hispanic White 1.00 Ref.
 Non-Hispanic Black 4.28 [3.29, 5.55] <0.001
 Hispanic 0.81 [0.51, 1.30] 0.38
 All other races 5.56 [3.99, 7.76] <0.001
Immigrant status, % (n)
 Born in United States 1.00 Ref.
 Born outside United States 3.03 [2.26, 4.07] <0.001
Marital status, % (n)
 Married or cohabitating 1.00 Ref.
 Never married 1.31 [0.96, 1.80] 0.09
 Widowed, divorced, or separated 1.11 [0.80, 1.53] 0.52
Education, % (n)
 College 1.00 Ref.
 High school graduate 1.07 [0.78, 1.47] 0.68
 Less than high school 1.05 [0.77, 1.43] 0.75
Income, M [95% CI] 0.85 [0.78, 0.92] <0.001
Blood transfusion, % (n)
 Yes 1.20 [0.83, 1.71] 0.33
 No 1.00 Ref.
Alcohol use, % (n)
 Yes 0.99 [0.78, 1.27] 0.97
 No 1.00 Ref.
Injection drug use, % (n)
 Yes 6.14 [3.98, 9.46] <0.001
 No 1.00 Ref.
Sexually transmitted infection, % (n)
 Yes 2.19 [1.06, 4.52] <0.05
 No 1.00 Ref.

Notes: OR = bivariate prevalence odds ratio; aOR = multivariable prevalence odds ratio; Ref. = reference.