Fig 4. Post-PCR clean-up was effective with either Mag-Bind® TotalPure NGS or NimaGen AmpliClean^TM beads.

(a) Overlayed fragment size profiles of sequencing libraries purified in parallel with each bead type. Sequencing and alignment data, including total number of raw reads (a), percentage of raw reads mapping to SARS-CoV-2 genome after primer-trimming (b), percentage coverage breadth (c) and mean coverage depth (d), for each sample following purification with each bead type, with the colour of points representing the mean Ct value from SARS-CoV-2 RT-qPCR of the sample.