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. 2023 Apr 14;18(4):e0284248. doi: 10.1371/journal.pone.0284248

Table 2. ICU admission and organic dysfunction.

Global AKI No AKI p
(n = 1642) (n = 618, 40.1%) (n = 923, 59.9%)
Diagnosis at admission
Viral pneumonia n (%) 1553 (94.6) 600 (97.1) 899 (97.4) 0.712
COPD exacerbation n (%) 16 (1) 8 (1.3) 8 (0.9) 0.417
Acute asthma n (%) 17 (1) 5 (0.8) 12 (1.3) 0.366
Heart failure n (%) 23 (1.4) 14 (2.3) 9 (1) 0.041
Other n (%) 47 (2.9) 134 (21.7) 103 (11.2) 0.362
Severity of the ARDS <0.001
Mild n (%) 127 (7.9) 28 (4.6) 92 (10.1)
Moderate n (%) 514 (32.7) 168 (27.5) 330 (36.3)
Severe n (%) 935 (59.4) 416 (68) 488 (53.6)
Organic dysfunction at admission
Shock n (%) 447 (27.2) 276 (44.7) 155 (16.8) <0.001
AKI n (%) 467 (28.4)
Hepatic failure n (%) 291 (17.7) 158 (25.6) 131 (14.2) <0.001
Coagulopathy n (%) 245 (14.9) 134 (21.7) 103 (11.2) <0.001
Neurological alteration n (%) 189 (11.5) 102 (16.5) 83 (9) <0.001
Thrombocytopenia n (%) 169 (19.3) 100 (16.2) 68 (7.4) <0.001

COPD- Chronic obstructive pulmonary disease

ARDS- Acute respiratory distress syndrome

AKI- Acute kidney injury.