Table 2.
Hazard ratio for major adverse cardiovascular events in patients with CHD (N = 1068)
| Model 1* | Model 2† | Modell 3‡ | Modell 4§ | |||||
|---|---|---|---|---|---|---|---|---|
| HR | P-value | HR | P-value | HR | P-value | HR | P-value | |
| Clinical insomnia(yes/no) | 1.62 (1.24, 2,11) | <0.001 | 1.49 (1.14, 1.97) | 0.004 | 1.48 (1.12, 1.96) | 0.006 | 1.41 (1.05, 1.89) | 0.023 |
| Bergen insomnia scale sum | 1.02 (1.01, 1.03) | <0.001 | 1.02 (1.01, 1.03) | 0.003 | 1.02 (1.00, 1.03) | 0.020 | 1.01 (1.00, 1.03) | 0.099 |
| OSA risk (yes/no) | 1.22 (0.92, 1.62) | 0.170 | – | – | – | |||
| Taking sleep medication past week (yes/no) | 0.87 (0.64, 1.19) | 0.443 | – | – | – |
All analyses based on imputed dataset. Insomnia and BIS are not imputed.
*Adjusted for age and gender, stratified for prior coronary events with combined estimates presented.
†Adjusted for coronary risk factors (CRP, smoking, LDL cholesterol, diabetes, physical activity, waist circumference, and systolic blood pressure), in addition to adjustments in Model 1.
‡Adjusted for cardiovascular comorbidity (stroke, peripheral artery disease, and kidney failure) in addition to adjustments in Model 2.
§Adjusted for Hospital Anxiety and Depression Scale (HADS) anxiety ≥ 8 and HADS depression ≥ 8 in addition to adjustments in Model 3. RR, relative risk.