Table 2.

Resistance frequencies of representative MRSA, VISA, VRSA, and LRSA isolates to TXA707 alone or in combination with oxacillin

Isolatea	Frequency of Resistance (FOR) to:
	4 μg/mL TXA707 Aloneb	4 μg/mL TXA707 + 2 μg/mL Oxacillinc
MRSA NRS705 (USA100)	2.59 × 10−8	<9.95 × 10−10
MRSA NRS643 (USA300)	7.49 × 10−9	4.28 × 10−10
VRSA VRS5	3.86 × 10−8	<6.02 × 10−10
VISA NRS27	5.75 × 10−8	<5.52 × 10−10
LRSA NRS127	4.46 × 10−8	<3.66 × 10−10

^aEach isolate is indicated by its NARSA designation

^b4 μg/mL TXA707 reflects 4x MIC

^c2 μg/mL oxacillin reflects the clinical breakpoint concentration of the drug for activity against S. aureus