Skip to main content
. Author manuscript; available in PMC: 2023 Apr 14.
Published in final edited form as: ACS Catal. 2020 Sep 2;10(18):10495–10499. doi: 10.1021/acscatal.0c02965

Table 1.

Initial Reaction Optimization

graphic file with name nihms-1839672-t0003.jpg
entry X additive 1 (%)a 1a (%)a conversion (%)b
1 Br - 17 23 40
2 Br 100 mg MS (4 Å) 18 1 20
3 Br 100 mg MS (4 Å), 0.5 equiv HE 32 2 35
4c I - 42 50 95
5c I 100 mg MS (4 Å) 46 8 59
6c I 100 mg MS (4 Å), 0.5 equiv HE 64 5 70
7 I 24 h, 100 mg MS (4 Å), 1 equiv HE
1.7 equiv amine, 4 equiv K3PO3 90 °C		 86 7 98
a

GC yield.

b

Based on unreacted aryl halide.

c

Reaction was conducted at 80 °C.

MS = molecular sieves.