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. 2023 Mar 31;14:1130933. doi: 10.3389/fimmu.2023.1130933

Figure 5.

Figure 5

ST2-deficient ILC2s fail to recruit eosinophils in acute lung inflammation. (A, C, D), Flow-cytometric plots showing ILC2s (A) in the Lung, eosinophils (C) in the lung or BAL (D) of untreated Ctrl (naïve) animals and papain treated Nmur1 iCre-eGFP Il1rl1 flox/flox mice (cKO) and littermate controls (Ctrl). Data are representative of two experiments with four to six mice per group. (B, E), Quantification of relative ILC2 (B) and eosinophil numbers from the lung or BAL (E) in the lung and BAL. (F), Quantification of relative resident and inflammatory eosinophil numbers in the lung. For (B, E, F): One-way ANOVA with multiple comparisons, ns, not significant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.