Figure 2. Time to Recurrent Seizure: LEV + VPA + CLB vs Other Triple Therapy.

1Number of patients at risk refers to the number of patients who have not experienced an event (i.e., the event treatment failure of the event death) at that particular time point (e.g., 3 months) and who are still at risk of experiencing an event (i.e., not censored). 2Patients who experienced treatment failure (due to adverse effects, withdrawal due to remission, or other reasons) before experiencing their recurrent seizure can no longer experience a recurrent seizure on their first-line monotherapy LEV or VPA, and therefore, treatment failure was handled as competing risk. CIF = cumulative incidence function; CLB = clobazam; LEV = levetiracetam; n = number of patients; VPA = valproic acid.