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. 2023 Feb 1;10(11):2206602. doi: 10.1002/advs.202206602

Figure 11.

Figure 11

A)(a) Quantitative microbiological analysis of cultured bone homogenates. (b) Representative radiographs of excised tibiae. Reproduced with permission.[ 131 ] Copyright 2005, American Society for Microbiology. B) Bacterial load in the femur in a model of osteomyelitis. Reproduced with permission.[ 132 ] Copyright 2004, Oxford University Press. C) Mean bacterial count at the implantation site after 7 days of treatment for MRSA‐induced osteomyelitis. (a) Increasing concentrations of LL18, including empty HG and VH‐loaded preparations (b) Increasing concentrations of VH‐loaded preparations with fixed LL18 concentrations. Reproduced with permission.[ 133 ] Copyright 2022, John Wiley & Sons. D) Survival rate in mice model. Reproduced under the terms of the CC BY 4.0 license.[ 135 ] Copyright 2021, Nature Publishing Group. E) (a) Lung bacterial load in a lung infection model. (b) Histological analysis of lung tissue. Reproduced with permission.[ 136 ] Copyright 2018, Elsevier. F) (a) Chimeric antimicrobial HnMc micelle protocol formulated with DSPE‐PEG‐HnMc and PLGA‐PEG. (b),(c) The mice survival and lung bacterial load after 16 days in a mice model of lung infection. Reproduced with permission.[ 137 ] Copyright 2020, American Chemical Society.