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. 2023 Feb 14;30(17):49779–49797. doi: 10.1007/s11356-023-25661-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Photomicrographs of a lateral view of the skull of the 19th day of gestation rat fetuses. A Control skull showing normally developed nasal (n), frontal (f), parietal (p), interparietal (ip), squamosal (sq), supraoccipital (so), premaxilla (pr-m), maxilla (m), and mandible (mn). B Skull of the fetus maternally treated with low dose MSG showing that cartilaginous and bony parts were faintly stained. C Skull of the fetus maternally treated with high-dose of MSG showing the absence of cartilage formation in all parts of the skull and delay in ossification of parietal (p) and interparietal (ip) bones. Note the reduction in skull size (8×)