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. 2023 Feb 14;30(17):49779–49797. doi: 10.1007/s11356-023-25661-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Photomicrographs of a lateral view of the hind limb of the 19th day of gestation rat fetuses. A Control hind limb showing, fully developed cartilage and bone of femur (fe), tibia (t), tarsals (tr), metatarsals (mt), and phalanges (ph). B Hind limb of the fetus maternally treated with a low dose of MSG shows a delay in chondrification of tarsals (ta) and phalanges (ph). C Hind limb of the fetus maternally treated with a high dose of MSG shows the complete absence of chondrification in the entire limb besides the absence of ossified phalanges (ph) (10X, 16 X)