Table 3.
Anthelmintic(s) | Study design | Selection bias | Performance bias | Detection bias | Attrition bias | Reporting bias | Risk of bias judgement | Reference |
---|---|---|---|---|---|---|---|---|
IVM | Comparative | N/A | N/A | No information | Low | Low | Low | Borgsteede et al. (1993) |
IVM | Comparative | N/A | N/A | No information | Low | Some concerns | Some concerns | von Samson-Himmelstjerna et al. (2007) |
IVM | Comparative | N/A | N/A | No information | Low | Low | Low | McFarlane et al. (2010) |
IVM | Randomised controlled | Low | No information | No information | Low | Low | Low | Larsen et al. (2011) |
IVM | Comparative | N/A | N/A | No information | Low | High | High | Zak et al. (2017) |
IVM | Comparative | N/A | N/A | No information | High | Some concerns | High | Rosanowski et al. (2017) |
IVM | Comparative | N/A | N/A | No information | Low | Low | Low | Molena et al. (2018) |
IVM | Comparative | Some concerns | Low | No information | High | No information | High | Butler et al. (2021) |
IVM, MOX | Comparative | Some concerns | No information | No information | Low | Low | Some concerns | Johnson and Biddle (2021) |
MOX | Comparative | Low | Some concerns | No information | Low | Some concerns | Some concerns | Abbas et al. (2021) |
IVM, MOX | Randomised controlled | No information | No information | No information | Low | Some concerns | Some concerns | (van Doorn et al., 2014) |
IVM, MOX | Retrospective | N/A | Some concerns | No information | No information | Low | Some concerns | Daniels and Proudman (2016) |
IVM, MOX, ABM | Comparative | No information | No information | No information | Low | Low | Low | Beasley et al. (2017) |
IVM, MOX, PYR, FBZ | Comparative | No information | No information | No information | Low | Some concerns | Some concerns | Relf et al. (2014) |
IVM, MOX | Randomised comparative | Low | No information | Low | Low | Low | Low | Geurden et al. (2014) |
IVM, MOX, PYR, FBZ | Comparative | Low | No information | Low | Low | Low | Low | Sanna et al. (2016) |
IVM, MOX | Comparative | Low | No information | No information | Low | Low | Low | Kooyman et al. (2016) |
MOX | Comparative | N/A | N/A | No information | Low | Low | Low | Tzelos et al. (2017) |
MOX, ABM | Randomised controlled | Low | No information | No information | Some concerns | Low | Some concerns | Holm-Martin et al. (2005) |
MOX, FBZ | Observational field | N/A | High | High | Low | Some concerns | High | Rossano et al. (2010) |
PYR | Comparative | N/A | N/A | No information | Low | No information | Low | Boersema et al. (1995) |
Abbreviations: ERP, egg reappearance period; N/A, not applicable; ALB, albendazole; ABM, abamectin; FBZ, fenbendazole; IVM, ivermectin; MOX, moxidectin; PYR, pyrantel.