Table 3.

Effect of interventions on various clinical assessment scales. Expressed in mean and standard deviations (S.D.). ∗ p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

Clinical variables	Groups	Baseline	30th day	60th day	BL–30th day	30th–60th day	BL–60th day	p value	Effect size (0–60 days)
IBS-SSS	KC	337.73 ± 63.91	289.09 ± 79.63	237.73 ± 96.06	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	0.002∗∗	2.09
	WS	360.43 ± 68.45	221.74 ± 75.05	74.35 ± 49.06	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
IBS-AR	KC	0a	0.05 ± 0.22	0.45 ± 0.5	0.31	0.005∗∗	0.003∗∗	<0.001∗∗∗	1.54
	WS	0a	0.25 ± 0.44	1 ± 0	0.008∗∗	<0.001∗∗∗	<0.001∗∗∗
GSRS	KC	15.68 ± 3.06	12.14 ± 2.85	8.95 ± 2.4	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	0.07	2.02
	WS	17.91 ± 4.42	10.22 ± 3.13	4.04 ± 1.74	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
IBS-VAS	KC	300 ± 86.9	353.18 ± 75.36	395.45 ± 80.75	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	3.82
	WS	310.43 ± 69.83	472.61 ± 66.07	605.65 ± 52.81	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
CSBM	KC	3.36 ± 1.09	4.73 ± 1.03	5.18 ± 1.4	<0.001∗∗∗	0.25	<0.001∗∗∗	<0.001∗∗∗	3.03
	WS	2.91 ± 1.08	7.3 ± 1.49	10.26 ± 2.56	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
BSF-D	KC	6.57 ± 0.53	6.57 ± 0.53	5.71 ± 0.48	0.31	0.004∗	0.004∗∗	<0.001∗∗∗	1.84
	WS	6.42 ± 0.53	5.57 ± 0.53	4.14 ± 0.37	0.008∗∗	0.009∗∗	0.008∗∗
BSF-C	KC	1.76 ± 0.43	1.84 ± 0.37	2.15 ± 0.37	0.317	0.04∗	0.02∗	<0.001∗∗∗	1.62
	WS	1.53 ± 0.51	2.46 ± 0.51	3.3 ± 0.63	0.004∗∗	0.001∗∗	0.001∗∗
HARS	KC	13.05 ± 3.9	10.59 ± 3.67	7.82 ± 3.5	0.003∗∗	<0.001∗∗∗	<0.001∗∗∗	0.34	1.81
	WS	15.57 ± 6.82	8.52 ± 4.79	3.13 ± 2.86	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
HDRS	KC	11.45 ± 2.92	8.5 ± 3.05	6.41 ± 2.5	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	0.441	1.18
	WS	12.91 ± 5.22	7.43 ± 3.35	3.7 ± 2.49	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
IBS-QOL	KC	96.55 ± 29.64	78.18 ± 27.49	62.55 ± 25.92	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗	0.168	2.02
	WS	107.91 ± 27.45	68.04 ± 20.77	33.43 ± 12.66	<0.001∗∗∗	<0.001∗∗∗	<0.001∗∗∗
Hb (g/dl)	KC	12.64 ± 1.34	–	13.07 ± 0.9	–	–	<0.001∗∗∗	0.31	–
	WS	13.07 ± 1.13	–	13.36 ± 0.98	–	–	<0.001∗∗∗
ESR (mm/h)	KC	19.59 ± 12.14	–	14.34 ± 6.75	–	–	0.94	0.84	–
	WS	14.91 ± 8.94	–	13.22 ± 8.11	–	–	<0.001∗∗∗
Presence of mucus in stool (number of patients)	KC	8	–	3	–	–	–	0.75b	–
	WS	4	–	1	–	–	–
Undigested food in stools (number of patients)	KC	11	–	8	–	–	–	0.85b	–
	WS	11	–	9	–	–	–

^a15th day assessment.

^bChi square test.