Fig. 9.

The regulatory network constructed in LUAD. A The upstream miRNAs of CENPO were predicted by miRDB, miRWalk, Targetscan and miRabel databases and the intersection was taken (82 intersection miRNAs). B Venn of 82 intersection miRNAs and 43 differently expressed miRNAs that were significantly related to the prognosis of patients with LUAD. C The Cytoscape-built regulatory network was constructed by Cytoscape, including CENPO, 82 miRNAs and 10 lncRNAs. D Survival analysis of 10 lncRNAs in the pancancer described by the forest plot. Functional enrichment pathways of CENPO based on the GSVA algorithm. E Top five positive enriched pathways based on the HALLMARK terms. F Four negative and one positive enriched pathway based on the KEGG terms