Table 1.
Effects of common psychotherapeutic drug classes on sleep
| Drug Class | Time to Sleep Onset | Sleep Continuity | Slow Wave Sleep | REM Sleep |
|---|---|---|---|---|
|
| ||||
| SSRI | Increased | Decreased | Decreased | Decreased |
|
| ||||
| SNRI | Unchanged | Decreased | Decreased | Decreased |
|
| ||||
| MAOI | Increased | Decreased | Unchanged | Decreased |
|
| ||||
| TCA | Decreased | Increased | Unchanged | Decreased |
|
| ||||
| Trazodone | Decreased | Increased | Increased | Decreased |
|
| ||||
| Antipsychotic | Decreased | Increased | Increased | Decreased |
|
| ||||
| Anxiolytic | Decreased | Increased | Decreased | Decreased |
These are general class effects on sleep. Each drug has its own profile.
Abbreviations: MAOI, monoamine oxidase inhibitor; SNRI, serotonin norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.
Adapted from Barkoukis TJ, Avidan AY, service) S (online. Review of Sleep Medicine; with permission.