Table 1.
Baseline characteristics for patients from the MR CLEAN cohort with histological analysis as compared to those without. ANOVA was performed; p-values > 0.05 are printed bold
| Histology n = 332, (%) | No histology n = 1194, (%) | p-value | |
|---|---|---|---|
| Age (median) | 70 | 71 | 0.690a |
| Sex (male) | 177 (53.3%) | 632 (52.9%) | 0.902 |
| NIHSS baseline (median) | 17 | 15 | 0.00a |
| IVT | 251 (75.6%) | 919 (77.2%) | 0.551 |
| Atrial fibrillation | 92 (27.9%) | 243 (20.7%) | 0.006 |
| Peripheral arterial disease | 43 (13.3%) | 95 (8.1%) | 0.004 |
| Previous stroke | 66 (19.9%) | 187 (15.8%) | 0.072 |
| Myocardial infarction | 55 (16.8%) | 178 (15.2%) | 0.486 |
| Antiplatelet use | 105 (32.2%) | 401 (34%) | 0.555 |
| Coumarin use | 54 (16.5%) | 140 (11.8%) | 0.025 |
| NOAC use | 11 (3.4%) | 26 (2.2%) | 0.228 |
| Occlusion segment based on CTA | |||
| Intracranial ICA | 12 (3.8%) | 73 (6.5%) | 0.072 |
| ICA-T | 90 (28.3%) | 232 (20.5%) | 0.003 |
| M1 | 190 (59.7%) | 652 (57.6%) | 0.502 |
| M2 | 25 (7.9%) | 156 (13.8%) | 0.005 |
| Other: M3/anterior | 1 (0.3%) | 18 (1.6%) | 0.077 |
| Etiology (TOAST) | |||
| Cardioembolic | 114 (34.3%) | 364 (30.5%) | 0.181 |
| Non-cardioembolic | 58 (17.5%) | 199 (16.7%) | 0.729 |
| Undetermined | 160 (48.2%) | 631 (52.8%) | 0.133 |
aMann-Whitney U test