Table 1.
Intra-donor variation. Displayed are mean, SD [nmol/109 platelets] and CV (coefficient of variation) for basal platelets (A) and lipid release upon thrombin stimulation (B).
| Lipid class | CE | Cer | FC | HexCer | LPC | LPE | PC | PC O | PE | PE P | PI | PS | SM | TG | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A) Basal platelets | |||||||||||||||
| Male n = 4 | Mean | 11.72 | 3.30 | 207.84 | 0.21 | 2.77 | 1.58 | 135.94 | 6.62 | 46.98 | 58.78 | 33.60 | 67.55 | 59.25 | 5.08 |
| SD | 11.79 | 0.15 | 45.89 | 0.00 | 0.68 | 0.46 | 18.50 | 0.37 | 3.06 | 1.86 | 10.18 | 4.59 | 4.97 | 7.19 | |
| CV [%] | 100.52 | 4.43 | 22.08 | 2.23 | 24.42 | 29.41 | 13.61 | 5.52 | 6.52 | 3.16 | 30.30 | 6.80 | 8.39 | 141.42 | |
| Female n = 5 | Mean | 10.74 | 3.05 | 200.37 | 0.18 | 2.48 | 1.26 | 137.63 | 6.48 | 46.54 | 55.95 | 29.14 | 66.98 | 56.25 | 6.62 |
| SD | 7.38 | 0.51 | 19.42 | 0.05 | 0.63 | 0.35 | 17.86 | 0.64 | 4.24 | 3.74 | 7.13 | 5.90 | 5.89 | 3.80 | |
| CV [%] | 68.72 | 16.86 | 9.69 | 27.75 | 25.41 | 27.73 | 12.97 | 9.86 | 9.12 | 6.68 | 24.46 | 8.81 | 10.47 | 57.43 | |
| B) Platelet release | |||||||||||||||
| Male n = 4 | Mean | 10.57 | 0.13 | 3.00 | 0.07 | 1.25 | 0.02 | 7.47 | 0.03 | 0.29 | 0.52 | 0.13 | 0.45 | 1.11 | 2.77 |
| SD | 10.30 | 0.02 | 4.25 | 0.02 | 0.05 | 0.01 | 6.62 | 0.01 | 0.16 | 0.43 | 0.07 | 0.47 | 0.74 | 3.92 | |
| CV [%] | 97.44 | 13.64 | 141.42 | 27.85 | 3.90 | 20.79 | 88.61 | 18.80 | 56.49 | 83.93 | 56.03 | 103.72 | 66.26 | 141.42 | |
| Female n = 5 | Mean | 8.34 | 0.12 | 3.35 | 0.04 | 1.27 | 0.06 | 6.71 | 0.03 | 0.50 | 0.71 | 0.11 | 1.55 | 1.08 | 2.51 |
| SD | 7.88 | 0.04 | 3.59 | 0.04 | 0.17 | 0.03 | 5.52 | 0.06 | 0.24 | 0.13 | 0.09 | 0.88 | 0.70 | 2.61 | |
| CV [%] | 94.56 | 33.24 | 107.24 | 99.53 | 13.07 | 61.11 | 82.34 | 185.08 | 48.19 | 18.54 | 86.22 | 57.17 | 65.09 | 103.94 | |