Table 1. Trials and data entered in the meta-analysis.
| Trial | vp | vn | cp | cn | year | vtm | vfb | ani | |
|---|---|---|---|---|---|---|---|---|---|
| Gonzaléz et al. (1989) | 6 | 227 | 29 | 198 | 1989 | b | f | m | |
| Nordhaug et al. (1994) | 0 | 58 | 6 | 44 | 1994 | b | f | h | |
| McClure et al. (1994) | 49 | 597 | 78 | 568 | 1994 | b | f | b | |
| Watson et al. (1996-1) | 104 | 605 | 136 | 634 | 1996 | b | f | m | |
| Watson et al. (1996-2) | 16 | 162 | 17 | 145 | 1996 | b | f | h | |
| Tenhagen et al. (2001) | 74 | 90 | 67 | 77 | 2001 | b | f | h | |
| Wilson et al. (2007) | 105 | 251 | 99 | 306 | 2007 | b | c | m | |
| Keskin et al. (2007) | 29 | 111 | 20 | 107 | 2007 | b | c | b | |
| Slobodanka et al. (2010) | 0 | 20 | 4 | 16 | 2010 | b | f | m | |
| Morimoto et al. (2011) | 54 | 235 | 50 | 245 | 2011 | b | c | b | |
| Magaš et al. (2013) | 0 | 20 | 2 | 20 | 2013 | b | f | m | |
| Maia et al. (2013) | 11 | 43 | 16 | 50 | 2013 | b | c | b | |
| Bradley et al. (2015-1) | 193 | 415 | 290 | 576 | 2015 | b | c | b | |
| Bradley et al. (2015-2) | 292 | 558 | 290 | 576 | 2015 | a | c | b | |
| Sayed et al. (2016) | 0 | 20 | 1 | 19 | 2015 | b | f | b | |
| Gorden et al. (2018-1) | 27 | 127 | 57 | 127 | 2017 | b | f | b | |
| Gorden et al. (2018-2) | 57 | 151 | 41 | 151 | 2017 | a | f | b | |
| Tashakkori et al. (2019) | 47 | 110 | 15 | 55 | 2019 | b | c | m | |
| Total cows in groups | 1,064 | 3,800 | 1,218 | 3,914 | |||||
| Overall total cows | 9,996 | ||||||||
In the calculation of the totals of animals entered in the analysis, the control from Bradley et al. (2015) were counted once only; vp: vaccinated developing CM; vn: vaccinate not developing CM; cp: control developing CM; cn: control not developing CM; vtm: vaccination timing (a: vaccinated after calving; b: vaccinated before calving); vfb: vaccine fabrication (c: commercial vaccine; f: self-fabrication); ani: animals used in the trial (h: heifers; m: multiparous; b: both).