Table 2.

Diagnostic criteria used for the diagnosis of frailty (Fried criteria)

Measure	Definition
Weight loss	Lost 4.5 kg or more unintentionally over the last year
Exhaustion	Self-report of either ‘felt that everything I did was an effort’ and/or ‘could not get going’ in the last week
Low physical activity	Self-report, equivalent to <90 kCal in women and <128 kCal in men
Slow walking	4 m at usual pace:
	speed <0.76 m/s for height <159 cm in women and <173 cm in men or speed <0.80 m/s for height >159 cm in women and >173 cm in men
Weakness	Grip strength
	Women: <17 kg for BMI <23 kg/m2; <17.3 kg for BMI 23.1–26 kg/m2; <18 kg for BMI 26.1–29 kg/m2; and <21 kg for BMI >29 kg/m2
	Men: <29 kg for BMI <24 kg/m2; <30 kg for BMI 24.1–26 kg/m2; <30 kg for BMI 26.1–28 kg/m2; <32 kg for BMI >28 kg/m2

Please note diagnostic thresholds for different criteria were modified for different population and different studies. At least 2/5 positive criteria defines pre-frailty and >3/5 criteria defines frailty.

BMI, body mass index.