Table 3.
Univariate analysis for local control per tumor
| Characteristics (comparison vs. reference) |
Hazard ratio | 95% confidence interval | p value |
|---|---|---|---|
|
BED category (BED10 ≥ 100 Gy vs. BED10 < 100 Gy) |
3.812 | 0.467–31.13 | 0.212 |
|
Diameter of metastatic lesion (continuous, per cm) |
1.383 | 0.557–3.436 | 0.484 |
| Location of metastatic lesion (right vs. left) | 5.869 | 0.721–47.75 | 0.098 |
|
Central nodule by RTOG criteria (yes vs. no) |
1.610 | 0.197–13.18 | 0.657 |
|
Abutment to the mediastinal structure (yes vs. no) |
No event for “yes” | 0.321* | |
| Extremity as primary site (yes vs. no) | 0.276 | 0.055–1.377 | 0.117 |
| Histological grade† (grade 3 vs. grade 2) | 2.853 | 0.528–15.41 | 0.223 |
|
Distant metastasis at initial diagnosis (yes vs. no) |
No event for “yes” | 0.639* | |
| Indication of SBRT | |||
| Oligoprogression vs. oligometastasis | 2.493 | 0.551–11.27 | 0.235 |
| Palliation vs. oligometastasis | 0.773 | 0.084–7.115 | 0.820 |
|
Single pulmonary lesion at recurrence (yes vs. no) |
0.711 | 0.170–2.983 | 0.641 |
|
Simultaneous extrathoracic metastasis (yes vs. no) |
2.885 | 0.679–12.26 | 0.151 |
|
Progression-free interval (> 1 year vs. ≤ 1 year) |
0.213 | 0.025–1.786 | 0.154 |
* This p value was calculated using log-rank test
† Calculated without cases with unknown value
BED10: Biologically effective dose with an α/β ratio of 10; RTOG: Radiation Therapy Oncology Group; SBRT: Stereotactic body radiation therapy