TABLE 1. Synoptic view of study cohort.
Identification no. | Donor type | Cause of death | Donor age (years) | Donor BMI | Liver weight (g) | Macrosteatosis (%) | Cold ischemia time (min) | Lactate clearance | Stable pH | Homogeneous perfusion | Artery flow >150 ml/min | PV flow >500 ml/min | Glucose metabolism | Bile production | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
tx_1 | DBD | Cerebrovascular | 79 | 35 | 1940 | 30 | 461 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_2 | DCDa | Cerebrovascular | 45 | 38 | 2140 | 35 | 248 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_3 | DBD | Cerebrovascular | 59 | 35 | 2700 | 40 | 315 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_4 | DBD | Cerebrovascular | 74 | 36 | 2600 | 30 | 241 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_5 | DBD | Anoxic brain injury | 72 | 53 | 2450 | 30 | 241 | ⨯ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | PNF |
tx_6 | DBD | Trauma | 50 | 25 | 2233 | 50 | 330 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_7 | DBD | Anoxic brain injury | 51 | 36 | 2381 | 60 | 103 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_8 | DBD | Anoxic brain injury | 49 | 34 | 2139 | 30 | 198 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_9 | DBD | Cerebrovascular | 63 | 22 | 1844 | 40 | 240 | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | Functioning |
tx_10 | DBD | Cerebrovascular | 68 | 27 | 1690 | 50 | 465 | ⨯ | ✓ | ✓ | ✓ | ✓ | ⨯ | ✓ | PNF |
disc_1 | DBD | Cerebrovascular | 79 | 37 | 2450 | 30 | 549 | ⨯ | ⨯ | ⨯ | ✓ | ✓ | ⨯ | ⨯ | Discarded |
disc_2 | DBD | Cerebrovascular | 48 | 35 | 2780 | 90 | 300 | ⨯ | ⨯ | ⨯ | ✓ | ✓ | ⨯ | ⨯ | Discarded |
disc_3 | DBD | Cerebrovascular | 64 | 34 | 3150 | 80 | 315 | ⨯ | ⨯ | ⨯ | ⨯ | ✓ | ⨯ | ✓ | Discarded |
disc_4 | DBD | Cerebrovascular | 68 | 34 | 2500 | 45 | 360 | ⨯ | ⨯ | ⨯ | ✓ | ✓ | ⨯ | ⨯ | Discarded |
Note: Lines in bold indicate livers that were transplanted and developed primary non‐function.
Abbreviations: BMI, body mass index; DBD, donation after brain death; DCD, donation after circulatory death; PNF, primary nonfunction; PV, portal vein.
Maastricht category 3 DCD donor. The liver was retrieved after a functional warm ischemia time of 65 minutes followed by 227 minutes of normothermic regional perfusion.