Table 3.
Predictive value of PRS-Sz and cannabis use on CAPE-42 subscales
| Independent variable | β | Std. error | p | R2 | |
|---|---|---|---|---|---|
| IMAGEN | |||||
| Depressive sub-scale | 0.065 | ||||
| PRS-Sz | 0.018 | 0.007 | 1.12 × 10−2 | ||
| Cannabis use | 0.010 | 0.004 | 2.47 × 10−2 | ||
| Negative sub-scale | 0.020 | ||||
| PRS-Sz | 0.014 | 0.007 | 5.28 × 10−2 | ||
| Cannabis use | 0.013 | 0.005 | 3.84 × 10−3 | ||
| Positive sub-scale | 0.021 | ||||
| PRS-Sz | 0.011 | 0.005 | 2.76 × 10−2 | ||
| Cannabis use | 0.004 | 0.003 | 1.68 × 10−1 | ||
| Utrecht | |||||
| Depressive sub-scale | 0.065 | ||||
| PRS-Sz | 0.022 | 0.007 | 1.10 × 10−3 | ||
| Cannabis use | 0.010 | 0.004 | 7.17 × 10−3 | ||
| Negative sub-scale | 0.033 | ||||
| PRS-Sz | 0.023 | 0.007 | 1.85 × 10−3 | ||
| Cannabis use | 0.019 | 0.004 | 7.17 × 10−6 | ||
| Positive sub-scale | 0.039 | ||||
| PRS-Sz | 0.011 | 0.006 | 5.88 × 10−2 | ||
| Cannabis use | 0.017 | 0.003 | 9.24 × 10−8 |
β, main effect size; std. error, standard error. Bold values indicate p < 0.05.
This table shows results of the effects of the independent variables in linear regression models on the various sub-scales of the CAPE-42. Dependent variable is log-transformed CAPE-42 scores for each subscale. We considered the first six PC and sex as covariates for all analyses and age is included for all analyses of the Utrecht cannabis cohort.