Table 2.
Total adversity exposure | Cases N = 384 | Controls N = 690 | Unadjusted OR | 95% CI | p | Adjusted ORa | 95% CI | p |
---|---|---|---|---|---|---|---|---|
None, N (%) | 213 (55.5) | 543 (78.7) | 1 | – | – | 1 | – | – |
One type, N (%) | 79 (20.6) | 96 (13.9) | 2.19 | 1.39–3.45 | <0.001 | 2.41 | 1.44–4.00 | 0.001 |
Two or more types, N (%) | 92 (24.0) | 51 (7.4) | 4.60 | 3.17–6.71 | <0.001 | 4.70 | 3.06–7.24 | <0.001 |
CI, confidence interval; OR, odds ratio.
Childhood adversity was measured by the CTQ dichotomised into at least one type of trauma reaching moderate to severe levels, or two or more of traumas reaching moderate to severe levels based on predefined cut-off scores from the CTQ manual (Bernstein et al., 1994).
Adjusted for site, sex, age at interview and years of education.