Figure 1.
Effects of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on retinal tissue perfusion (A) RTP and blood flow (B) RBF in mild diabetic retinopathy patients with methylenetetrahydrofolate reductase polymorphisms (DR + PM) patients receiving the medical food during follow-up periods. In patients with A1298C mutation, all vascular metrics (including RTP and RBF) were improved over the Baseline at 4 months and 6 months, but the peak benefit was at four months (all P < 0.05). In patients with C677T and C677T/A1298C compound mutations, RTP at 6 months significantly increased as compared to those at baseline and 4 months. Bars = standard error.
