Table 1.

Cost per Gram of Monoclonal Antibodies in the Finished Product, as Reimbursed by CMS (Source: https://www.cms.gov]

Monoclonal Antibody	Price per Gram
Inotuzumab ozogam	$24,430,000
Ranibizumab	$2,584,000
Alemtuzumab	$2,207,000
Gemtuzumab ozogamicin	$2,147,900
Inebilizumab-cdon	$462,000
Burosumab-twza	$402,000
Faricimab-svoa	$380,000
Emapalumab-lzsg	$375,710
Brolucizumab-dbll	$313,790
Mogamulizumab-kpkc	$216,390
Basiliximab	$205,100
Benralizumab	$169,460
Ipilimumab	$163,000
Ustekinumab sc	$163,000
Brentuximab vedotin	$162,840
Enfortumab vedo-ejfv	$130,160
Polatuzumab vedotin	$118,000
Emicizumab-kxwh	$99,500
Adalimumab	$69,250
Pembrolizumab	$54,540
Nivolumab/Realtimab	$45,160
Teprotumumab-trbw	$38,200
Ado-trastuzumab emt	$35,690
Evinacumab-dgnb	$34,550
Tezepelumab-ekko	$32,182
Nivolumab	$29,540
Cemiplimab-rwlc	$27,580
Trastuzumab deru-nxki	$25,210
Cranzilumab	$25,000
Natalizumab	$23,820
Eculizumab	$22,770
Denosumab	$22,510
Ravulizumab	$22,227
Dostarlimab-gxly	$22,000
Tezepelumab-ekko	$17,870
Anifrolumab-fnia	$16,160
Risankizumab-rzaa	$15,800
Pertuzumab	$14,140
Golimumab iv	$14,081
Panitumumab	$13,900
Bebtelovimab	$13,680
Ramucirumab	$13,124
Sacituzumab govitecan-hziy	$12,800
Ustekinumab iv	$12,360
Romosozumab-aqqg	$9970
Amivantamab-vmjw	$9445
Margetuximab-cmkb	$8800
Trastuzumab excl biosimi	$8444
Rituximab-abbs	$8273
Durvalumab	$7795
Isatuximab-irfc	$7040
Ibalizumab-uiyk	$6973
Bevacizumab-awwb	$6972
Elotuzumab	$6950
Herceptin hylecta	$6782
Obinutuzumab	$6735
Tafasitamab-cxix	$6450
Ofatumumab	$6395
Tocilizumab	$6166
Daratumumab	$5935
Necitumumab	$5700
Certolizumab pegol	$5061
Belimumab	$4947
Daratumumab hyaluronidase	$4676
Atezolizumab	$3989
Rituximab hyaluronidase	$3787
Infliximab not biosimilar	$3502