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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Pain. 2023 May 1;164(5):1148–1157. doi: 10.1097/j.pain.0000000000002813

Table 2.

Unstimulated and LPS-stimulated cytokine values by COPC status.

IC/BPS only(n=36) IC/BPS+ COPC(n=99) All(n=135)
median 25th – 75thpercentile median 25th – 75thpercentile median 25th – 75thpercentile
Unstimulated (pg/ml)
monocyte chemoattractant protein-1 118 78–156 103 78–148 109 78–151
macrophage inflammatory protein 1-alphaa 58 36–136 36 36–108 36 36–112
Interleukin-1β 1 1–2 1 <1–3 1 <1–3
Interleukin-6a 1 1–1 1 1–1 1 1–1
Interleukin-8 37 23–68 37 37–79 37 37–77
Interleukin-10a <1 <1−<1 <1 <1−<1 <1 <1−<1
Tumor necrosis factor – α 4 3–5 5 5–6 4 4–6
Stimulated (pg/ml) (
monocyte chemoattractant protein-1 1182 896–1658 1715 1033–2542 1526 1000–2310
macrophage inflammatory protein 1-alpha 38497 23818–58503 48184 37793–75389 45923 33951–72730
Interleukin-1β 5427 4195–9035 8982 4686–14479 8309 4316–8309
Interleukin-6 14605 10209–21923 21218 15739–25878 20244 14374–25815
Interleukin-8 11793 7197–15349 14812 9316–20675 12550 9004–19368
Interleukin-10 53 24–83 68 41–107 65 37–98
Tumor necrosis factor – α 3807 2294–5648 4448 2899–5591 4123 2715–5591
a

> than 25% of values below limit of quantification