Table 2.

Risk of incident cardiomyopathy and related outcomes associated with increased sphericity index.

	Cardiomyopathy		Atrial fibrillation		Heart failure		Cardiac arrest
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Model 1 Age, sex	1.57 (1.27-1.94)	<0.001	1.35 (1.28-1.42)	<0.001	1.37 (1.24-1.53)	<0.001	1.17 (0.88-1.54)	0.3
Model 2 Model 1 + BMI, pulse rate, HTN, DM, prior MI	1.62 (1.30-2.03)	<0.001	1.31 (1.23-1.38)	<0.001	1.23 (1.10-1.38)	<0.001	1.08 (0.81-1.44)	0.6
Model 3a Model 2 + LVEF	1.51 (1.13-2.02)	0.005	1.23 (1.15-1.32)	<0.001	1.11 (0.96-1.28)	0.2	1.01 (0.73-1.41)	0.9
Model 3b Model 2 + LVEDVi	1.46 (1.09-1.97)	0.01	1.19 (1.11-1.28)	<0.001	1.13 (0.97-1.31)	0.1	0.94 (0.67-1.34)	0.7
Model 3c Model 2 + LVESVi	1.47 (1.09-1.97)	0.01	1.19 (1.11-1.28)	<0.001	1.09 (0.94-1.26)	0.3	0.92 (0.65-1.31)	0.7
Model 4 Model 2 + LVEF, LVESVi	1.47 (1.10-1.98)	0.01	1.20 (1.11-1.28)	<0.001	1.09 (0.94-1.26)	0.3	0.92 (0.65-1.31)	0.7

Hazard ratios (HR) reported per 1 standard deviation increase in sphericity index.

BMI = body mass index, HTN = hypertension, DM = diabetes mellitus, MI = myocardial infarction, LVEF = left ventricular ejection fraction, LVEDVi = left ventricular end-diastolic volume indexed on body surface area, LVESVi = left ventricular end-systolic volume indexed on body surface area