Table 1.
Participant Characteristics
| Bulk RNA | snRNA DLPFC | SRM DLPFC | TMT DLPFC | |||
|---|---|---|---|---|---|---|
| DLPFC | PCC | CN | ||||
| N | 208 | 490 | 673 | 48 | 1084 | 375 |
| Age at death (yrs)1 | 90±6 | 89±7 | 89±6 | 87±6 | 89±6 | 89±6 |
| Education (yrs) | 16±4 | 16±4 | 16±4 | 19±3 | 16±4 | 16±4 |
| Global Cognition | −0.8±1.2 | −0.67±1.03 | −0.74±1.08 | −1.12±1.37 | −0.84±1.13 | −0.53±1.05 |
| Average Follow-up (yrs) | 9.38±5.87 | 7.51±4.86 | 7.69±4.84 | 7.9±4.68 | 8.12±5.11 | 8.79±4.48 |
| % Male | 36% | 38% | 36% | 50% | 33% | 30% |
| % NHW2 | 95% | 96% | 97% | 92% | 96% | 96% |
| % APOE4 positive | 26% | 25% | 27% | 27% | 25% | 20% |
| % AD | 41% | 38% | 40% | 46% | 45% | 33% |
1
Values are mean ± SD or percentage as indicated.
2
NHW=non-Hispanic White