TABLE 1.
Amino acid changes detected in structural proteins of SARS‐CoV2 strains circulated in the sixth wave of the pandemic which were detected in more than 70% of each variant and compared to shared aa changes during the first five waves in Iran.
| Genes | 6th wave | Shared changes with previous waves | |||||||
|---|---|---|---|---|---|---|---|---|---|
| BA.1 | BA.2 | ML | 1st | 2nd | 3rd | 4th | 5th | ||
| Structural proteins | S |
D614G D796Y E484A G142D G339D H655Y K417N N440K N501Y N679K N764K N856K N969K P681H Q493R Q498R Q954H S371L S373P S375F S477N T478K T547K Y505H |
D405N D614G D796Y E484A G142D G339D H655Y K417N N440K N501Y N679K N969K P681H Q493R Q498R Q954H R408S S373P S375F S477N T376A T478K V213G Y505H P26DEL P25DEL A27S L24DEL |
D614G D796Y E484A G142D G339D H655Y K417N N440K N501Y N679K N969K P681H Q493R Q498R Q954H S371L S373P S375F S477N T478K T547K Y505H P26DEL P25DEL A27S L24DEL |
D614G |
D614G |
D614G N501Y P681H |
D614G T478K G142D |
|
| E | T9I | T9I | T9I | ||||||
| M |
A63T D3G Q19E |
A63T Q19E |
A63T D3G Q19E |
||||||
| N |
R203K G204R |
R203K G204R |
R203K G204R |
||||||