Table 2.

Overview of mCOPE Intervention Components by Session.

Intervention Component	Session 1	Session 2	Session 3	Session 4	Session 5
Content by Videoconference Session	•Introductions •Study overview •Study rationale and presentation of Neuromatrix Theory •Progressive Muscle Relaxation •Home Practice Assignment	•Home Practice Review •Activity/Rest Cycle •Pleasant Activity Planning •Home Practice Assignment	•Home Practice Review •Revisit Neuromatrix Theory •Cognitive Restructuring •Calming Self-Statements •Home Practice Assignment	•Home Practice Review •Mini-relaxation practice •Pleasant Imagery •Home Practice Assignment	•Home Practice Review •Skill Review and Practice Moving Forward •Identification of Benefits, Problem Solving Barriers to Continued Skill Practice •Goal Setting •Wrap-up, Patient Feedback
Mobile Application Features by Session	•Demonstration Video: Progressive Muscle Relaxation •Audio Guidance: Brief and Full-Length Progressive Muscle Relaxation •Message Reminder: Practice Progressive Muscle Relaxation	•Video Explanation: Activity-Rest Cycle •Video Explanation: Pleasant Activity Planning •Video Demonstration: Pleasant Activity Planning •Journal Entry Activity: Pleasant Activity •Message Reminder: Practice Activity Rest Cycle •Tailored Message: Practice Pleasant Activities from Journal Entry •Message Reminder: Practice Progressive Muscle Relaxation	•Video Explanation: Positive Thinking •Video Example: Positive Thinking •Video Explanation: Calming Self-Statements •Journal Entry Activity: Calming Self Statement •Tailored Message: Calming Self-Statement from Journal Entry	•Audio Guidance: Pleasant Imagery •Audio Guidance: Mini-Relaxation Practice •Message Reminder: Practice Mini-Relaxation •Message Reminder: Practice Pleasant Imagery	•Video Explanation: Goal Setting •Text/In-app Reminder: Practice Mini-Relaxation •Message Reminder: Practice Pleasant Imagery
Videoconference Elements Across Sessions	•Screen sharing to jointly view session handouts •Review of previously taught skills and home practice (problem solving, encouragement) •Applied skill practice and debriefing •Planning for home practice
Mobile Application Features Across Sessions	•New mobile app content release tied to date of scheduled sessions •PDF of session handouts •Section for patient to add notes •Overview of tasks to complete between sessions •Caring in-app messages with general encouragement 2x/week •Brief assessment of patient-reported pain, fatigue and stress 3x/week •Brief assessment of patient-reported coping skill use 1x/week •Personalized messages based on self-report ratings of pain, fatigue and stress 3x/week •Message reminder for upcoming sessions •Message reminder for brief assessments •Ability to review content from previous sessions