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. 2022 Oct 27;164(5):1128–1137. doi: 10.1097/j.pain.0000000000002811

Table 3.

Direct and indirect mediation effects of sleep condition, N3 sleep, and cellular inflammation on heat pain threshold.

Variable Direct effects Indirect effects
FA-US N3 sleep Inflammation FA-US/N3 sleep FA-US/inflammation FA-US/N3 sleep/inflammation
Heat pain threshold −0.43 (−1.24 to 0.38) 0.00 (−0.01 to 0.01) −0.02* (−0.04 to −0.01) -0.24 (-0.64 to 0.15) −0.02 (−0.45 to 0.39) −0.15* (−0.30 to −0.03)

Values are unstandardized coefficients and 95% confidence intervals. Covariates include sex, age, BMI, Black race, and Hispanic or Latino ethnicity. *P < .05.