Table 3.

Regression analysis to identify associations of clinicodemographic characteristics with risk of hemorrhagic transformation after intravenous thrombolysis^a.

Characteristic	OR (95%CI)	p
Age	0.97 (0.94–1.00)	0.144
Atrial fibrillation	5.52 (2.51–12.15)	<0.001
Baseline NIHSS score	1.05 (1.00–1.10)	0.044
Baseline diastolic blood pressure	1.00 (0.98–1.02)	0.507
Platelet count	0.99 (0.99–1.00)	0.534
Hyperlipidemia	0.60 (0.29–1.24)	0.173
INR	0.41 (0.01–10.78)	0.594
Total CSVD score ≥ 1	2.87 (1.38–5.94)	0.005

^aAdjusted for total cerebral small vessel disease burden.

Boldfaced values indicate statistically significant independent risk factors.

OR, odds ratio; CI, confidence interval; INR, international normalized ratio; NIHSS, National Institutes of Health Stroke Scale; CSVD, cerebral small vessel disease.